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ZyCoV-D: Decoding the Science behind India’s Plasmid DNA Vaccine & What Makes it Special

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Zydus Cadila’s ZyCoV-D could well become the world’s first DNA vaccine for human use and the first vaccine in India to be licensed for adolescents.

A year ago, the term ‘plasmid’ may have generated little interest among people. And nobody would have associated DNA with vaccines. But on July 1, 2021, this changed, even if momentarily, when Ahmedabad-based Zydus Cadila announced that it had applied for emergency use authorisation of its COVID-19 vaccine, ZyCoV-D, which is set to become the world’s first plasmid DNA vaccine for human use.